An investigator wants to estimate caffeine consumption in high school students
guru2009<tableborder="0" cellpadding="0" cellspacing="0" width="64" style="fontfamily: Verdana, arial, sansserif; lineheight: normal; width: 48pt;">1. Suppose we want to design a new placebocontrolled trial to evaluate an experimental medication to increase lung capacity. The primary outcome is peak expiratory flow rate, a continuous variable measured in liters per minute. The primary outcome will be measured after 6 months on treatment. The expected peak expiratory flow rate in adults is 300 with a standard deviation of 50. How many subjects should be enrolled to ensure 80% power to detect a difference of 15 liters per minute with a two sided test and a=0.05?
2. An investigator wants to estimate caffeine consumption in high school students. How many students would be required to ensure that a 95% confidence interval estimate for the mean caffeine intake (measured in mg) is within 15 units of the true mean? Assume that the standard deviation in caffeine intake is 68 mg.

 6 years ago
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Biostatistics in Public Health Ch 8 & 9 Problems
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1. Suppose we want to design a new placebocontrolled trial to evaluate an experimental medication to increase lung capacity. The primary outcome is peak expiratory flow rate, a … 6 years ago